Melatonin Antagonizes Nickel-Induced Aerobic Glycolysis by Blocking ROS-Mediated HIF-1α/miR210/ISCU Axis Activation

Nickel and its compounds, which are well-documented carcinogens, induce the Warburg effect in normal cells by stabilizing hypoxia-inducible factor 1α (HIF-1α). Melatonin has shown diverse anticancer properties for its reactive oxygen species- (ROS-) scavenging ability. Our aim was to explore how mel...

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Detalles Bibliográficos
Autores principales: He, Mindi, Zhou, Chao, Lu, Yonghui, Mao, Ling, Xi, Yu, Mei, Xiang, Wang, Xue, Zhang, Lei, Yu, Zhengping, Zhou, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275958/
https://www.ncbi.nlm.nih.gov/pubmed/32566089
http://dx.doi.org/10.1155/2020/5406284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275958/
https://www.ncbi.nlm.nih.gov/pubmed/32566089
http://dx.doi.org/10.1155/2020/5406284

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