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COVID-19 Critical Illness Pathophysiology Driven by Diffuse Pulmonary Thrombi and Pulmonary Endothelial Dysfunction Responsive to Thrombolysis

Critically ill COVID-19 patients have relatively well-preserved lung mechanics despite severe gas exchange abnormalities, a feature not consistent with classical ARDS but more consistent with pulmonary vascular disease. Patients with severe COVID-19 also demonstrate markedly abnormal coagulation, wi...

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Detalles Bibliográficos
Autores principales: Poor, Hooman D., Ventetuolo, Corey E., Tolbert, Thomas, Chun, Glen, Serrao, Gregory, Zeidman, Amanda, Dangayach, Neha S., Olin, Jeffrey, Kohli-Seth, Roopa, Powell, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276060/
https://www.ncbi.nlm.nih.gov/pubmed/32511632
http://dx.doi.org/10.1101/2020.04.17.20057125