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FTY720 ameliorates GvHD by blocking T lymphocyte migration to target organs and by skin fibrosis inhibition

BACKGROUND: Fibrosis is the formation of excess connective tissue in an organ or tissue during a reparative or reactive process. Graft-versus-host disease (GvHD) is a medical complication of allogeneic tissue transplantation with transplanted donor T cell-mediated inflammatory response; it is charac...

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Detalles Bibliográficos
Autores principales: Ryu, Jaeyoon, Jhun, Jooyeon, Park, Min-Jung, Baek, Jin-ah, Kim, Se-Young, Cho, Keun-Hyung, Choi, Jeong-Won, Park, Sung-Hwan, Choi, Jong Young, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276082/
https://www.ncbi.nlm.nih.gov/pubmed/32505218
http://dx.doi.org/10.1186/s12967-020-02386-w