Kynurenine pathway modulation reverses the experimental autoimmune encephalomyelitis mouse disease progression

BACKGROUND: Multiple sclerosis (MS) is a chronic immune-mediated disorder of the central nervous system characterized by demyelination, neuroinflammation, and neurodegeneration. Activation of the kynurenine pathway (KP) results from acute and chronic neuroinflammation leading to both immune suppress...

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Detalles Bibliográficos
Autores principales: Sundaram, Gayathri, Lim, Chai K., Brew, Bruce J., Guillemin, Gilles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276083/
https://www.ncbi.nlm.nih.gov/pubmed/32505212
http://dx.doi.org/10.1186/s12974-020-01844-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276083/
https://www.ncbi.nlm.nih.gov/pubmed/32505212
http://dx.doi.org/10.1186/s12974-020-01844-y

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