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Kynurenine pathway modulation reverses the experimental autoimmune encephalomyelitis mouse disease progression

BACKGROUND: Multiple sclerosis (MS) is a chronic immune-mediated disorder of the central nervous system characterized by demyelination, neuroinflammation, and neurodegeneration. Activation of the kynurenine pathway (KP) results from acute and chronic neuroinflammation leading to both immune suppress...

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Detalles Bibliográficos
Autores principales:	Sundaram, Gayathri, Lim, Chai K., Brew, Bruce J., Guillemin, Gilles J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276083/ https://www.ncbi.nlm.nih.gov/pubmed/32505212 http://dx.doi.org/10.1186/s12974-020-01844-y

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