Ischemia/hypoxia inhibits cardiomyocyte autophagy and promotes apoptosis via the Egr-1/Bim/Beclin-1 pathway

BACKGROUND: Myocardial injury caused by microvascular obstruction (MVO) is characterized by persistent ischemia/hypoxia (IH) of cardiomyocytes after microembolization. Autophagy and Egr-1 were closely associated with various cardiovascular diseases, including MVO. Bim and Beclin-1 are the important...

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Detalles Bibliográficos
Autores principales: Su, Bo, Wang, Xian-Tao, Sun, Yu-Han, Long, Man-Yun, Zheng, Jing, Wu, Wen-Hao, Li, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276312/
https://www.ncbi.nlm.nih.gov/pubmed/32547612
http://dx.doi.org/10.11909/j.issn.1671-5411.2020.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276312/
https://www.ncbi.nlm.nih.gov/pubmed/32547612
http://dx.doi.org/10.11909/j.issn.1671-5411.2020.05.004

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