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BRCA immunohistochemistry for screening of BRCA mutation in epithelial ovarian cancer patients

To evaluate BRCA1/2 immunohistochemistry (IHC) as a screening test for germline BRCA1/2 in epithelial ovarian cancer (EOC), tumor tissue from 105 EOC patients who had germline BRCA mutations, including 9 BRCA1 mutations, 6 BRCA2 mutations and 90 no BRCA mutations, were studied. Paraffin-embedded tis...

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Detalles Bibliográficos
Autores principales: Manchana, Tarinee, Tantbirojn, Patou, Pohthipornthawat, Natkrita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276421/
https://www.ncbi.nlm.nih.gov/pubmed/32529018
http://dx.doi.org/10.1016/j.gore.2020.100582