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Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization
The precise characterization and quantification of oxidative protein damage is a significant challenge due to the low abundance, large variety, and heterogeneity of modifications. Mass spectrometry (MS)-based techniques at the peptide level (proteomics) provide a detailed but limited picture due to...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276450/ https://www.ncbi.nlm.nih.gov/pubmed/32505089 http://dx.doi.org/10.1016/j.redox.2020.101586 |