Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork

The eukaryotic replisome, organized around the Cdc45-MCM-GINS (CMG) helicase, orchestrates chromosome replication. Multiple factors associate directly with CMG, including Ctf4 and the heterotrimeric fork protection complex (Csm3/Tof1 and Mrc1), which has important roles including aiding normal repli...

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Detalles Bibliográficos
Autores principales: Baretić, Domagoj, Jenkyn-Bedford, Michael, Aria, Valentina, Cannone, Giuseppe, Skehel, Mark, Yeeles, Joseph T.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276988/
https://www.ncbi.nlm.nih.gov/pubmed/32369734
http://dx.doi.org/10.1016/j.molcel.2020.04.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276988/
https://www.ncbi.nlm.nih.gov/pubmed/32369734
http://dx.doi.org/10.1016/j.molcel.2020.04.012

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