Novel Broccoli Sulforaphane-Based Analogues Inhibit the Progression of Pancreatic Cancer without Side Effects

The naturally occurring isothiocyanate sulforaphane, found in Brassicaceae vegetables, is promising in cancer treatment, e.g., by the normalization of enhanced levels of NF-κB-signaling in tumor stem cells. We chemically synthesized seven sulforaphane analogues by substitution of the sulfinyl group...

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Detalles Bibliográficos
Autores principales: Georgikou, Christina, Buglioni, Laura, Bremerich, Maximilian, Roubicek, Nico, Yin, Libo, Gross, Wolfgang, Sticht, Carsten, Bolm, Carsten, Herr, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277136/
https://www.ncbi.nlm.nih.gov/pubmed/32429039
http://dx.doi.org/10.3390/biom10050769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277136/
https://www.ncbi.nlm.nih.gov/pubmed/32429039
http://dx.doi.org/10.3390/biom10050769

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