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Novel Broccoli Sulforaphane-Based Analogues Inhibit the Progression of Pancreatic Cancer without Side Effects
The naturally occurring isothiocyanate sulforaphane, found in Brassicaceae vegetables, is promising in cancer treatment, e.g., by the normalization of enhanced levels of NF-κB-signaling in tumor stem cells. We chemically synthesized seven sulforaphane analogues by substitution of the sulfinyl group...
Autores principales: | Georgikou, Christina, Buglioni, Laura, Bremerich, Maximilian, Roubicek, Nico, Yin, Libo, Gross, Wolfgang, Sticht, Carsten, Bolm, Carsten, Herr, Ingrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277136/ https://www.ncbi.nlm.nih.gov/pubmed/32429039 http://dx.doi.org/10.3390/biom10050769 |
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