C-Methylation of S-adenosyl-L-Methionine Occurs Prior to Cyclopropanation in the Biosynthesis of 1-Amino-2-Methylcyclopropanecarboxylic Acid (Norcoronamic Acid) in a Bacterium

Many pharmacologically important peptides are bacterial or fungal in origin and contain nonproteinogenic amino acid (NPA) building blocks. Recently, it was reported that, in bacteria, a cyclopropane-containing NPA 1-aminocyclopropanecarboxylic acid (ACC) is produced from the L-methionine moiety of S...

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Detalles Bibliográficos
Autores principales: Maruyama, Chitose, Chinone, Yukiko, Sato, Shusuke, Kudo, Fumitaka, Ohsawa, Kosuke, Kubota, Junya, Hashimoto, Junko, Kozone, Ikuko, Doi, Takayuki, Shin-ya, Kazuo, Eguchi, Tadashi, Hamano, Yoshimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277169/
https://www.ncbi.nlm.nih.gov/pubmed/32429436
http://dx.doi.org/10.3390/biom10050775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277169/
https://www.ncbi.nlm.nih.gov/pubmed/32429436
http://dx.doi.org/10.3390/biom10050775

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