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Differentiation of Murine C2C12 Myoblasts Strongly Reduces the Effects of Myostatin on Intracellular Signaling

Alongside in vivo models, a simpler and more mechanistic approach is required to study the effects of myostatin on skeletal muscle because myostatin is an important negative regulator of muscle size. In this study, myostatin was administered to murine (C2C12) and human (CHQ) myoblasts and myotubes....

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Detalles Bibliográficos
Autores principales: Lautaoja, Juulia H., Pekkala, Satu, Pasternack, Arja, Laitinen, Mika, Ritvos, Olli, Hulmi, Juha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277184/
https://www.ncbi.nlm.nih.gov/pubmed/32365803
http://dx.doi.org/10.3390/biom10050695