Abnormal Hypermethylation of CpG Dinucleotides in Promoter Regions of Matrix Metalloproteinases Genes in Breast Cancer and its Relation to Epigenomic Subtypes and HER2 Overexpression

Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) substantially contribute to the regulation of intercellular interactions and thereby play a role in maintaining the tissue structure and function. We examined methylation of a subset of 5’-cytosine-phosphate-guanine-3’ (CpG) dinucl...

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Detalles Bibliográficos
Autores principales: Simonova, Olga A., Kuznetsova, Ekaterina B., Tanas, Alexander S., Rudenko, Viktoria V., Poddubskaya, Elena V., Kekeeva, Tatiana V., Trotsenko, Ivan D., Larin, Sergey S., Kutsev, Sergei I., Zaletaev, Dmitry V., Nemtsova, Marina V., Strelnikov, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277193/
https://www.ncbi.nlm.nih.gov/pubmed/32397602
http://dx.doi.org/10.3390/biomedicines8050116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277193/
https://www.ncbi.nlm.nih.gov/pubmed/32397602
http://dx.doi.org/10.3390/biomedicines8050116

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