Cargando…

Abnormal Hypermethylation of CpG Dinucleotides in Promoter Regions of Matrix Metalloproteinases Genes in Breast Cancer and its Relation to Epigenomic Subtypes and HER2 Overexpression

Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) substantially contribute to the regulation of intercellular interactions and thereby play a role in maintaining the tissue structure and function. We examined methylation of a subset of 5’-cytosine-phosphate-guanine-3’ (CpG) dinucl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simonova, Olga A., Kuznetsova, Ekaterina B., Tanas, Alexander S., Rudenko, Viktoria V., Poddubskaya, Elena V., Kekeeva, Tatiana V., Trotsenko, Ivan D., Larin, Sergey S., Kutsev, Sergei I., Zaletaev, Dmitry V., Nemtsova, Marina V., Strelnikov, Vladimir V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277193/ https://www.ncbi.nlm.nih.gov/pubmed/32397602 http://dx.doi.org/10.3390/biomedicines8050116

Ejemplares similares

Abnormal promoter DNA hypermethylation of the integrin, nidogen, and dystroglycan genes in breast cancer
por: Strelnikov, Vladimir V., et al.
Publicado: (2021)

Methylation of the BIN1 gene promoter CpG island associated with breast and prostate cancer
por: Kuznetsova, Ekaterina B, et al.
Publicado: (2007)

Clinical relevance of somatic mutations in main driver genes detected in gastric cancer patients by next-generation DNA sequencing
por: Nemtsova, Marina V., et al.
Publicado: (2020)

Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice
por: Nemtsova, Marina V., et al.
Publicado: (2017)

Application Areas of Traditional Molecular Genetic Methods and NGS in relation to Hereditary Urological Cancer Diagnosis
por: Mikhaylenko, Dmitry S., et al.
Publicado: (2020)

Parental Origin of the RB1 Gene Mutations in Families with Low Penetrance Hereditary Retinoblastoma
por: Alekseeva, Ekaterina A., et al.
Publicado: (2021)

Preservation of methylated CpG dinucleotides in human CpG islands
por: Panchin, Alexander Y., et al.
Publicado: (2016)

DNA Methylation and Prospects for Predicting the Therapeutic Effect of Neoadjuvant Chemotherapy for Triple-Negative and Luminal B Breast Cancer
por: Sigin, Vladimir O., et al.
Publicado: (2023)

Roles of E-cadherin and Noncoding RNAs in the Epithelial–mesenchymal Transition and Progression in Gastric Cancer
por: Bure, Irina V., et al.
Publicado: (2019)

DNA methylation markers panel can improve prediction of response to neoadjuvant chemotherapy in luminal B breast cancer
por: Sigin, Vladimir O., et al.
Publicado: (2020)

The Heterogeneous Landscape and Early Evolution of Pathogen-Associated CpG Dinucleotides in SARS-CoV-2
por: Di Gioacchino, Andrea, et al.
Publicado: (2021)

Mutations in Epigenetic Regulation Genes in Gastric Cancer
por: Nemtsova, Marina V., et al.
Publicado: (2021)

Case of Hereditary Papillary Renal Cell Carcinoma Type I in a Patient With a Germline MET Mutation in Russia
por: Mikhaylenko, Dmitry S., et al.
Publicado: (2020)

CpG island hypermethylation go circular (RNA)
por: Dragomir, Mihnea P., et al.
Publicado: (2018)

CpG Island Mapping by Epigenome Prediction
por: Bock, Christoph, et al.
Publicado: (2007)

DEAF1 Binds Unmethylated and Variably Spaced CpG Dinucleotide Motifs
por: Jensik, Philip J., et al.
Publicado: (2014)

Less is more: Biased loss of CpG dinucleotides strengthens antiviral immunity
por: Sauter, Daniel, et al.
Publicado: (2021)

Aberrant CpG Islands Hypermethylation Profiles in Malignant Gliomas
por: Kim, Kwang Ryeol, et al.
Publicado: (2014)

Hypermethylation of the DLC1 CpG island does not alter gene expression in canine lymphoma
por: Bryan, Jeffrey N, et al.
Publicado: (2009)

Somatic Mutation Analyses in Studies of the Clonal Evolution and Diagnostic Targets of Prostate Cancer
por: Mikhaylenko, Dmitry S., et al.
Publicado: (2017)

Methylation-mediated deamination of 5-methylcytosine appears to give rise to mutations causing human inherited disease in CpNpG trinucleotides, as well as in CpG dinucleotides
por: Cooper, David N, et al.
Publicado: (2010)

Methylation profiling of carcinogenesis-associated genes in sporadic breast cancer
por: Nemtsova, M, et al.
Publicado: (2005)

Depletion of CpG Dinucleotides in Papillomaviruses and Polyomaviruses: A Role for Divergent Evolutionary Pressures
por: Upadhyay, Mohita, et al.
Publicado: (2015)

Mutation dynamics of CpG dinucleotides during a recent event of vertebrate diversification
por: Pértille, Fábio, et al.
Publicado: (2019)

Long noncoding RNA landscapes specific to benign and malignant thyroid neoplasms of distinct histological subtypes
por: Yakushina, Valentina D., et al.
Publicado: (2021)

Genomic insights into cancer-associated aberrant CpG island hypermethylation
por: Sproul, Duncan, et al.
Publicado: (2013)

CpG Island Hypermethylation in Gastric Carcinoma and Its Premalignant Lesions
por: Kang, Gyeong Hoon
Publicado: (2012)

Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
por: Bae, Min Gyun, et al.
Publicado: (2016)

High Resolution Detection and Analysis of CpG Dinucleotides Methylation Using MBD-Seq Technology
por: Lan, Xun, et al.
Publicado: (2011)

Parvovirus B19 DNA CpG Dinucleotide Methylation and Epigenetic Regulation of Viral Expression
por: Bonvicini, Francesca, et al.
Publicado: (2012)

Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication
por: Antzin-Anduetza, Irati, et al.
Publicado: (2017)

The CpG dinucleotide content of the HIV-1 envelope gene may predict disease progression
por: Wasson, Mishi Kaushal, et al.
Publicado: (2017)

Identifying hypermethylated CpG islands using a quantile regression model
por: Sun, Shuying, et al.
Publicado: (2011)

Circular RNA CpG island hypermethylation-associated silencing in human cancer
por: Ferreira, Humberto J., et al.
Publicado: (2018)

Predicting DNA Methylation State of CpG Dinucleotide Using Genome Topological Features and Deep Networks
por: Wang, Yiheng, et al.
Publicado: (2016)

Testosterone Depletion Induces Demethylation of Murine Reelin Promoter CpG Dinucleotides: A Preliminary Study
por: da Silva, Victor Augusto Moraes, et al.
Publicado: (2015)

Zika Virus with Increased CpG Dinucleotide Frequencies Shows Oncolytic Activity in Glioblastoma Stem Cells
por: Trus, Ivan, et al.
Publicado: (2020)

CXXC5 as an unmethylated CpG dinucleotide binding protein contributes to estrogen-mediated cellular proliferation
por: Ayaz, Gamze, et al.
Publicado: (2020)

Variability in Codon Usage in Coronaviruses Is Mainly Driven by Mutational Bias and Selective Constraints on CpG Dinucleotide
por: Daron, Josquin, et al.
Publicado: (2021)

Epigenetic Changes in the Pathogenesis of Rheumatoid Arthritis
por: Nemtsova, Marina V., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2734q6r161t8v7imiik2ias2ch