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When Less Is More: Specific Capture and Analysis of Tumor Exosomes in Plasma Increases the Sensitivity of Liquid Biopsy for Comprehensive Detection of Multiple Androgen Receptor Phenotypes in Advanced Prostate Cancer Patients

We evaluated the advantages and the reliability of novel protocols for the enrichment of tumor extracellular vesicles (EVs), enabling a blood-based test for the noninvasive parallel profiling of multiple androgen receptor (AR) gene alterations. Three clinically relevant AR variants related to respon...

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Detalles Bibliográficos
Autores principales: Foroni, Chiara, Zarovni, Natasa, Bianciardi, Laura, Bernardi, Simona, Triggiani, Luca, Zocco, Davide, Venturella, Marta, Chiesi, Antonio, Valcamonico, Francesca, Berruti, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277361/
https://www.ncbi.nlm.nih.gov/pubmed/32455948
http://dx.doi.org/10.3390/biomedicines8050131