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Spironolactone and XPB: An Old Drug with a New Molecular Target

Spironolactone (SP) is commonly used for the treatment of heart failure, hypertension, and complications of cirrhosis by antagonizing the mineralocorticoid receptor. However, SP also antagonizes the androgen receptor, and thus SP has also been shown to be effective in the treatment of acne, hair los...

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Detalles Bibliográficos
Autores principales: Gabbard, Ryan D., Hoopes, Robert R., Kemp, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277409/
https://www.ncbi.nlm.nih.gov/pubmed/32414008
http://dx.doi.org/10.3390/biom10050756