Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase

Antisense oligonucleotides conjugated with boron clusters (B-ASOs) have been described as potential gene expression inhibitors and carriers of boron for boron neutron capture therapy (BNCT), providing a dual-action therapeutic platform. In this study, we tested the nucleolytic stability of DNA oligo...

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Detalles Bibliográficos
Autores principales: Kaniowski, Damian, Kulik, Katarzyna, Ebenryter-Olbińska, Katarzyna, Wielgus, Ewelina, Lesnikowski, Zbigniew, Nawrot, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277537/
https://www.ncbi.nlm.nih.gov/pubmed/32380792
http://dx.doi.org/10.3390/biom10050718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277537/
https://www.ncbi.nlm.nih.gov/pubmed/32380792
http://dx.doi.org/10.3390/biom10050718

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