Cargando…

Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase

Antisense oligonucleotides conjugated with boron clusters (B-ASOs) have been described as potential gene expression inhibitors and carriers of boron for boron neutron capture therapy (BNCT), providing a dual-action therapeutic platform. In this study, we tested the nucleolytic stability of DNA oligo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaniowski, Damian, Kulik, Katarzyna, Ebenryter-Olbińska, Katarzyna, Wielgus, Ewelina, Lesnikowski, Zbigniew, Nawrot, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277537/ https://www.ncbi.nlm.nih.gov/pubmed/32380792 http://dx.doi.org/10.3390/biom10050718

Ejemplares similares

Boron Clusters as Enhancers of RNase H Activity in the Smart Strategy of Gene Silencing by Antisense Oligonucleotides
por: Kaniowski, Damian, et al.
Publicado: (2022)

High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents (‡)
por: Kaniowski, Damian, et al.
Publicado: (2017)

Composites of Nucleic Acids and Boron Clusters (C(2)B(10)H(12)) as Functional Nanoparticles for Downregulation of EGFR Oncogene in Cancer Cells
por: Kaniowski, Damian, et al.
Publicado: (2021)

EGFR-Targeted Cellular Delivery of Therapeutic Nucleic Acids Mediated by Boron Clusters
por: Kaniowski, Damian, et al.
Publicado: (2022)

Metallacarborane Synthons for Molecular Construction—Oligofunctionalization of Cobalt Bis(1,2-dicarbollide) on Boron and Carbon Atoms with Extendable Ligands
por: Śmiałkowski, Krzysztof, et al.
Publicado: (2023)

C5-substituents of uridines and 2-thiouridines present at the wobble position of tRNA determine the formation of their keto-enol or zwitterionic forms - a factor important for accuracy of reading of guanosine at the 3΄-end of the mRNA codons
por: Sochacka, Elzbieta, et al.
Publicado: (2017)

The evolution and structure of snake venom phosphodiesterase (svPDE) highlight its importance in venom actions
por: Pan, Cheng-Tsung, et al.
Publicado: (2023)

Formation of an RNA Quadruplex-Duplex Hybrid in Living Cells between mRNA of the Epidermal Growth Factor Receptor (EGFR) and a G-Rich Antisense Oligoribonucleotide
por: Gudanis, Dorota, et al.
Publicado: (2020)

Different Oxidation Pathways of 2-Selenouracil and 2-Thiouracil, Natural Components of Transfer RNA
por: Kulik, Katarzyna, et al.
Publicado: (2020)

2-Selenouridine, a Modified Nucleoside of Bacterial tRNAs, Its Reactivity in the Presence of Oxidizing and Reducing Reagents
por: Kulik, Katarzyna, et al.
Publicado: (2022)

The Effect of Stereochemistry on Sodium Ion Complexation in Nucleoside-Metallacarborane Conjugates
por: Olejniczak, Agnieszka B., et al.
Publicado: (2010)

Metallacarborane Derivatives Effective against Pseudomonas aeruginosa and Yersinia enterocolitica
por: Swietnicki, Wieslaw, et al.
Publicado: (2021)

Mechanisms of Vascular Damage by Hemorrhagic Snake Venom Metalloproteinases: Tissue Distribution and In Situ Hydrolysis
por: Baldo, Cristiani, et al.
Publicado: (2010)

Metallacarboranes as tunable redox potential electrochemical indicators for screening of gene mutation
por: García-Mendiola, Tania, et al.
Publicado: (2016)

Snakes, Snake Venoms, and Antivenenes
por: Ranck, E. M.
Publicado: (1902)

The Sequence and a Three-Dimensional Structural Analysis Reveal Substrate Specificity among Snake Venom Phosphodiesterases
por: Ullah, Anwar, et al.
Publicado: (2019)

Researches on Snake-Venom
por: Mitchell, S. Weir
Publicado: (1885)

Snake Venoms in Medicine
por: Chopra, R. N., et al.
Publicado: (1932)

Snake Venom in Therapeutics
Publicado: (1937)

Pharmacokinetics of Snake Venom
por: Sanhajariya, Suchaya, et al.
Publicado: (2018)

Escherichia coli tRNA 2-Selenouridine Synthase (SelU): Elucidation of Substrate Specificity to Understand the Role of S-Geranyl-tRNA in the Conversion of 2-Thio- into 2-Selenouridines in Bacterial tRNA
por: Szczupak, Patrycja, et al.
Publicado: (2022)

From Endotoxin to Snake Venom
por: Spink, Wesley W.
Publicado: (1958)

Studies on sea snake venom
por: TAMIYA, Nobuo, et al.
Publicado: (2011)

Dr. Fayrer on Venomous Snakes
Publicado: (1872)

The Toxic Principles of Snake-Venoms
por: Richards, Vincent
Publicado: (1887)

Sterilization of Snake Venom Preparations
por: Chopra, R. N., et al.
Publicado: (1942)

Snake Venoms in Pharmacology and Therapeutics
por: Chopra, R. N., et al.
Publicado: (1935)

The Sterility of Snake Venom Solutions
por: Pasricha, C. L., et al.
Publicado: (1941)

Venomous Snakes—A Request
por: Stirling, Alex. W.
Publicado: (1897)

Venomous Snakes—A Request
por: Sterling, Alex W.
Publicado: (1897)

Toxinology and Pharmacology of Snake Venoms
por: Križaj, Igor
Publicado: (2023)

Venom Ophthalmia and Ocular Complications Caused by Snake Venom
por: Chang, Kun-Che, et al.
Publicado: (2020)

Metallacarborane Cluster Anions of the Cobalt Bisdicarbollide-Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides
por: Chen, Yao, et al.
Publicado: (2023)

Proteopeptidomic, Functional and Immunoreactivity Characterization of Bothrops moojeni Snake Venom: Influence of Snake Gender on Venom Composition
por: Amorim, Fernanda Gobbi, et al.
Publicado: (2018)

TOXINS AND ANTITOXINS--SNAKE VENOMS AND ANTIVENINS
por: Madsen, Th., et al.
Publicado: (1907)

Snake Venom Disintegrins and Cell Migration
por: Selistre-de-Araujo, Heloisa S., et al.
Publicado: (2010)

Recombinant snake venom prothrombin activators
por: Lövgren, Ann
Publicado: (2013)

Routine Treatment of Epilepsy, with Snake Venom
por: Chowhan, J. S.
Publicado: (1940)

Massage in the Treatment of Venomous Snake-Bites
por: Nicholls, Lucius
Publicado: (1928)

Snake Venom as a Therapeutic Agent
por: Wall, F.
Publicado: (1919)

Cannot write session to /tmp/vufind_sessions/sess_ts0e8pdclerqmp40n4egcseu9n