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Remarkable Levels of (15)N Polarization Delivered through SABRE into Unlabeled Pyridine, Pyrazine, or Metronidazole Enable Single Scan NMR Quantification at the mM Level
[Image: see text] While many drugs and metabolites contain nitrogen, harnessing their diagnostic (15)N NMR signature for their characterization is underutilized because of inherent detection difficulties. Here, we demonstrate how precise ultralow field signal amplification by reversible exchange (±0...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277555/ https://www.ncbi.nlm.nih.gov/pubmed/32383603 http://dx.doi.org/10.1021/acs.jpcb.0c02583 |