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D-Loop Mutation G42A/G46A Decreases Actin Dynamics

Depolymerization and polymerization of the actin filament are indispensable in eukaryotes. The DNase I binding loop (D-loop), which forms part of the interface between the subunits in the actin filament, is an intrinsically disordered loop with a large degree of conformational freedom. Introduction...

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Detalles Bibliográficos
Autores principales: Matsuzaki, Mizuki, Fujiwara, Ikuko, Kashima, Sae, Matsumoto, Tomoharu, Oda, Toshiro, Hayashi, Masahito, Maeda, Kayo, Takiguchi, Kingo, Maéda, Yuichiro, Narita, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277580/
https://www.ncbi.nlm.nih.gov/pubmed/32397190
http://dx.doi.org/10.3390/biom10050736