Computational Investigations on the Binding Mode of Ligands for the Cannabinoid-Activated G Protein-Coupled Receptor GPR18

GPR18 is an orphan G protein-coupled receptor (GPCR) expressed in cells of the immune system. It is activated by the cannabinoid receptor (CB) agonist ∆(9)-tetrahydrocannabinol (THC). Several further lipids have been proposed to act as GPR18 agonists, but these results still require unambiguous conf...

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Detalles Bibliográficos
Autores principales: Neumann, Alexander, Engel, Viktor, Mahardhika, Andhika B., Schoeder, Clara T., Namasivayam, Vigneshwaran, Kieć-Kononowicz, Katarzyna, Müller, Christa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277601/
https://www.ncbi.nlm.nih.gov/pubmed/32365486
http://dx.doi.org/10.3390/biom10050686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277601/
https://www.ncbi.nlm.nih.gov/pubmed/32365486
http://dx.doi.org/10.3390/biom10050686

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