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Synthesis of pyrrolidinedione-fused hexahydropyrrolo[2,1-a]isoquinolines via three-component [3 + 2] cycloaddition followed by one-pot N-allylation and intramolecular Heck reactions

Two kinds of [3 + 2] cycloaddition intermediates generated from the three-component reactions of 2-bromobenzaldehydes and maleimides with amino esters or amino acids were used for a one-pot N-allylation and intramolecular Heck reactions to form pyrrolidinedione-fused hexahydropyrrolo[2,1-a]isoquinol...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoming, Meng, Suzhi, Zhang, Xiaofeng, Zhang, Qiang, Yan, Shenghu, Zhang, Yue, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277624/
https://www.ncbi.nlm.nih.gov/pubmed/32550934
http://dx.doi.org/10.3762/bjoc.16.106