How Can Biomolecules Improve Mucoadhesion of Oral Insulin? A Comprehensive Insight using Ex-Vivo, In Silico, and In Vivo Models

Currently, insulin can only be administered through the subcutaneous route. Due to the flaws associated with this route, it is of interest to orally deliver this drug. However, insulin delivered orally has several barriers to overcome as it is degraded by the stomach’s low pH, enzymatic content, and...

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Detalles Bibliográficos
Autores principales: Amaral, Mariana, Martins, Ana Sofia, Catarino, José, Faísca, Pedro, Kumar, Pradeep, Pinto, João F., Pinto, Rui, Correia, Isabel, Ascensão, Lia, Afonso, Ricardo A., Gaspar, M. Manuela, Charmier, Adília J., Figueiredo, Isabel Vitória, Reis, Catarina Pinto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277740/
https://www.ncbi.nlm.nih.gov/pubmed/32349416
http://dx.doi.org/10.3390/biom10050675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277740/
https://www.ncbi.nlm.nih.gov/pubmed/32349416
http://dx.doi.org/10.3390/biom10050675

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