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MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer’s Disease Therapy

Microtubule affinity-regulating kinase (MARK4) plays a key role in Alzheimer’s disease (AD) development as its overexpression is directly linked to increased tau phosphorylation. MARK4 is a potential drug target of AD and is thus its structural features are employed in the development of new therape...

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Detalles Bibliográficos
Autores principales: Shamsi, Anas, Anwar, Saleha, Mohammad, Taj, Alajmi, Mohamed F., Hussain, Afzal, Rehman, Md. Tabish, Hasan, Gulam Mustafa, Islam, Asimul, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277793/
https://www.ncbi.nlm.nih.gov/pubmed/32443670
http://dx.doi.org/10.3390/biom10050789