Cargando…
MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer’s Disease Therapy
Microtubule affinity-regulating kinase (MARK4) plays a key role in Alzheimer’s disease (AD) development as its overexpression is directly linked to increased tau phosphorylation. MARK4 is a potential drug target of AD and is thus its structural features are employed in the development of new therape...
Autores principales: | Shamsi, Anas, Anwar, Saleha, Mohammad, Taj, Alajmi, Mohamed F., Hussain, Afzal, Rehman, Md. Tabish, Hasan, Gulam Mustafa, Islam, Asimul, Hassan, Md. Imtaiyaz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277793/ https://www.ncbi.nlm.nih.gov/pubmed/32443670 http://dx.doi.org/10.3390/biom10050789 |
Ejemplares similares
-
Unraveling Binding Mechanism of Alzheimer’s Drug Rivastigmine Tartrate with Human Transferrin: Molecular Docking and Multi-Spectroscopic Approach towards Neurodegenerative Diseases
por: Shamsi, Anas, et al.
Publicado: (2019) -
Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: possible implication in COVID-19 therapy
por: Shamsi, Anas, et al.
Publicado: (2020) -
Identification of high-affinity inhibitors of SARS-CoV-2 main protease: Towards the development of effective COVID-19 therapy
por: Mohammad, Taj, et al.
Publicado: (2020) -
Multispectroscopic and Molecular Docking Insight into
Elucidating the Interaction of Irisin with Rivastigmine Tartrate:
A Combinational Therapy Approach to Fight Alzheimer’s Disease
por: Waseem, Rashid, et al.
Publicado: (2021) -
Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition
por: Anwar, Saleha, et al.
Publicado: (2020)