Hemistepsin A Inhibits Cell Proliferation and Induces G0/G1-Phase Arrest, Cellular Senescence and Apoptosis Via the AMPK and p53/p21 Signals in Human Hepatocellular Carcinoma

Hemistepsin A (HsA), a natural sesquiterpene lactone isolated from Hemistepta lyrata, has been known as a wide range of anti-tumor effects. The aim of this study was to determine whether HsA suppresses hepatocellular carcinoma (HCC) and to figure out the cellular signaling pathways involved in the a...

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Detalles Bibliográficos
Autores principales: Baek, Su Youn, Hwang, Ui Wook, Suk, Ho Young, Kim, Young Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277854/
https://www.ncbi.nlm.nih.gov/pubmed/32375410
http://dx.doi.org/10.3390/biom10050713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277854/
https://www.ncbi.nlm.nih.gov/pubmed/32375410
http://dx.doi.org/10.3390/biom10050713

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