Bone marrow mesenchymal stem cell-derived endothelial cells increase capillary density and accelerate angiogenesis in mouse hindlimb ischemia model

BACKGROUND: Mesenchymal stem cells (MSCs) can improve limb perfusion and increase vessel density in a murine model of hindlimb ischemia. But low engraftment rate of those cells limited their therapeutic effect. Endothelial cells (ECs) play an important role in neovascularization. And MSCs can differ...

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Detalles Bibliográficos
Autores principales: Yao, Ziping, Liu, Huihui, Yang, Min, Bai, Yun, Zhang, Bihui, Wang, Chengen, Yan, Ziguang, Niu, Guochen, Zou, Yinghua, Li, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278145/
https://www.ncbi.nlm.nih.gov/pubmed/32513272
http://dx.doi.org/10.1186/s13287-020-01710-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278145/
https://www.ncbi.nlm.nih.gov/pubmed/32513272
http://dx.doi.org/10.1186/s13287-020-01710-x

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