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Analysis of 1321 Eubacterium rectale genomes from metagenomes uncovers complex phylogeographic population structure and subspecies functional adaptations

BACKGROUND: Eubacterium rectale is one of the most prevalent human gut bacteria, but its diversity and population genetics are not well understood because large-scale whole-genome investigations of this microbe have not been carried out. RESULTS: Here, we leverage metagenomic assembly followed by a...

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Detalles Bibliográficos
Autores principales: Karcher, Nicolai, Pasolli, Edoardo, Asnicar, Francesco, Huang, Kun D., Tett, Adrian, Manara, Serena, Armanini, Federica, Bain, Debbie, Duncan, Sylvia H., Louis, Petra, Zolfo, Moreno, Manghi, Paolo, Valles-Colomer, Mireia, Raffaetà, Roberta, Rota-Stabelli, Omar, Collado, Maria Carmen, Zeller, Georg, Falush, Daniel, Maixner, Frank, Walker, Alan W., Huttenhower, Curtis, Segata, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278147/
https://www.ncbi.nlm.nih.gov/pubmed/32513234
http://dx.doi.org/10.1186/s13059-020-02042-y