Caffeine prevents hyperoxia-induced lung injury in neonatal mice through NLRP3 inflammasome and NF-κB pathway

BACKGROUND: Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in premature infants and hyperoxia exposure is a major cause. In hyperoxic lung injury animal model, alveolar simplification and pro-inflammatory cells infiltration are the main pathophysiologic changes. Caffeine is a drug...

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Detalles Bibliográficos
Autores principales: Chen, Shangqin, Wu, Qiuping, Zhong, Dingjuan, Li, Changchong, Du, Lizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278162/
https://www.ncbi.nlm.nih.gov/pubmed/32513156
http://dx.doi.org/10.1186/s12931-020-01403-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278162/
https://www.ncbi.nlm.nih.gov/pubmed/32513156
http://dx.doi.org/10.1186/s12931-020-01403-2

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