Mesenchymal stem cell-derived exosomes improve motor function and attenuate neuropathology in a mouse model of Machado-Joseph disease

BACKGROUND: Machado-Joseph disease is the most common autosomal dominant hereditary ataxia worldwide without effective treatment. Mesenchymal stem cells (MSCs) could slow the disease progression, but side effects limited their clinical application. Besides, MSC-derived exosomes exerted similar effic...

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Detalles Bibliográficos
Autores principales: You, Hua-Jing, Fang, Shu-Bin, Wu, Teng-Teng, Zhang, Hongyu, Feng, Yu-Kun, Li, Xue-Jiao, Yang, Hui-Hua, Li, Ge, Li, Xun-Hua, Wu, Chao, Fu, Qing-Ling, Pei, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278177/
https://www.ncbi.nlm.nih.gov/pubmed/32513306
http://dx.doi.org/10.1186/s13287-020-01727-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278177/
https://www.ncbi.nlm.nih.gov/pubmed/32513306
http://dx.doi.org/10.1186/s13287-020-01727-2

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