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Unstructured Biology of Proteins from Ubiquitin-Proteasome System: Roles in Cancer and Neurodegenerative Diseases

The 26S proteasome is a large (~2.5 MDa) protein complex consisting of at least 33 different subunits and many other components, which form the ubiquitin proteasomal system (UPS), an ATP-dependent protein degradation system in the cell. UPS serves as an essential component of the cellular protein su...

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Detalles Bibliográficos
Autores principales: Gadhave, Kundlik, Kumar, Prateek, Kapuganti, Shivani K., Uversky, Vladimir N., Giri, Rajanish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278180/
https://www.ncbi.nlm.nih.gov/pubmed/32455657
http://dx.doi.org/10.3390/biom10050796