Effect of deletion of gene cluster involved in synthesis of Enterobacterial common antigen on virulence and immunogenicity of live attenuated Salmonella vaccine when delivering heterologous Streptococcus pneumoniae antigen PspA

BACKGROUND: Enterobacterial common antigen (ECA) is a family-specific surface antigen shared by all members of the Enterobacteriaceae family. Previous studies showed that the loss of ECA results in Salmonella attenuation, indicating its usefulness as a vaccine candidate for Salmonella infection, but...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Qing, Shen, Xuegang, Bian, Xiaoping, Kong, Qingke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278252/
https://www.ncbi.nlm.nih.gov/pubmed/32513100
http://dx.doi.org/10.1186/s12866-020-01837-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278252/
https://www.ncbi.nlm.nih.gov/pubmed/32513100
http://dx.doi.org/10.1186/s12866-020-01837-0

Ejemplares similares