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ACE2 diversity in placental mammals reveals the evolutionary strategy of SARS-CoV-2

The recent emergence of SARS-CoV-2 is responsible for the current pandemic of COVID-19, which uses the human membrane protein ACE2 as a gateway to host-cell infection. We performed a comparative genomic analysis of 70 ACE2 placental mammal orthologues to identify variations and contribute to the und...

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Detalles Bibliográficos
Autores principales: Fam, Bibiana S.O., Vargas-Pinilla, Pedro, Amorim, Carlos Eduardo G., Sortica, Vinicius A., Bortolini, Maria Cátira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278419/
https://www.ncbi.nlm.nih.gov/pubmed/32520981
http://dx.doi.org/10.1590/1678-4685-GMB-2020-0104