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Broad-spectrum antifungal activities and mechanism of drimane sesquiterpenoids

Eight drimane sesquiterpenoids including (-)-drimenol and (+)-albicanol were synthesized from (+)-sclareolide and evaluated for their antifungal activities. Three compounds, (-)-drimenol, (+)-albicanol, and (1R,2R,4aS,8aS)-2-hydroxy-2,5,5,8a-tetramethyl-decahydronaphthalene-1-carbaldehyde (4) showed...

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Detalles Bibliográficos
Autores principales: Edouarzin, Edruce, Horn, Connor, Paudyal, Anuja, Zhang, Cunli, Lu, Jianyu, Tong, Zongbo, Giaever, Guri, Nislow, Corey, Veerapandian, Raja, Hua, Duy H., Vediyappan, Govindsamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278516/
https://www.ncbi.nlm.nih.gov/pubmed/32548177
http://dx.doi.org/10.15698/mic2020.06.719