Preclinical validation of a novel metastasis‐inhibiting Tie1 function‐blocking antibody

The angiopoietin (Ang)–Tie pathway has been intensely pursued as candidate second‐generation anti‐angiogenic target. While much of the translational work has focused on the ligand Ang2, the clinical efficacy of Ang2‐targeting drugs is limited and failed to improve patient survival. In turn, the orph...

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Detalles Bibliográficos
Autores principales: Singhal, Mahak, Gengenbacher, Nicolas, La Porta, Silvia, Gehrs, Stephanie, Shi, Jingjing, Kamiyama, Miki, Bodenmiller, Diane M, Fischl, Anthony, Schieb, Benjamin, Besemfelder, Eva, Chintharlapalli, Sudhakar, Augustin, Hellmut G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278563/
https://www.ncbi.nlm.nih.gov/pubmed/32302470
http://dx.doi.org/10.15252/emmm.201911164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278563/
https://www.ncbi.nlm.nih.gov/pubmed/32302470
http://dx.doi.org/10.15252/emmm.201911164

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