Protein Formulations Containing Polysorbates: Are Metal Chelators Needed at All?

Proteins are prone to post-translational modifications at specific sites, which can affect their physicochemical properties, and consequently also their safety and efficacy. Sources of post-translational modifications include oxygen and reactive oxygen species. Additionally, catalytic amounts of Fe(...

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Detalles Bibliográficos
Autores principales: Brovč, Ema Valentina, Pajk, Stane, Šink, Roman, Mravljak, Janez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278585/
https://www.ncbi.nlm.nih.gov/pubmed/32443662
http://dx.doi.org/10.3390/antiox9050441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278585/
https://www.ncbi.nlm.nih.gov/pubmed/32443662
http://dx.doi.org/10.3390/antiox9050441

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