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Protein Formulations Containing Polysorbates: Are Metal Chelators Needed at All?
Proteins are prone to post-translational modifications at specific sites, which can affect their physicochemical properties, and consequently also their safety and efficacy. Sources of post-translational modifications include oxygen and reactive oxygen species. Additionally, catalytic amounts of Fe(...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278585/ https://www.ncbi.nlm.nih.gov/pubmed/32443662 http://dx.doi.org/10.3390/antiox9050441 |