N-Acetyl-Cysteine Regenerates Albumin Cys34 by a Thiol-Disulfide Breaking Mechanism: An Explanation of Its Extracellular Antioxidant Activity

In the present paper, the extracellular antioxidant activity of N-acetyl-cysteine (NAC) is explained by considering its ability to regenerate the free form of albumin Cys34 by breaking the disulfide bond of the cysteinylated form (HSA-Cys). NAC’s capability to regenerate albumin Cys34 (HSA-SH) was s...

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Detalles Bibliográficos
Autores principales: Altomare, Alessandra, Baron, Giovanna, Brioschi, Maura, Longoni, Martina, Butti, Riccardo, Valvassori, Edoardo, Tremoli, Elena, Carini, Marina, Agostoni, Piergiuseppe, Vistoli, Giulio, Banfi, Cristina, Aldini, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278672/
https://www.ncbi.nlm.nih.gov/pubmed/32354002
http://dx.doi.org/10.3390/antiox9050367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278672/
https://www.ncbi.nlm.nih.gov/pubmed/32354002
http://dx.doi.org/10.3390/antiox9050367

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