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Discovery of GLO1 New Related Genes and Pathways by RNA-Seq on A2E-Stressed Retinal Epithelial Cells Could Improve Knowledge on Retinitis Pigmentosa

Endogenous antioxidants protect cells from reactive oxygen species (ROS)-related deleterious effects, and an imbalance in the oxidant/antioxidant systems generates oxidative stress. Glyoxalase 1 (GLO1) is a ubiquitous cellular enzyme involved in detoxification of methylglyoxal (MG), a cytotoxic bypr...

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Detalles Bibliográficos
Autores principales: Donato, Luigi, Scimone, Concetta, Alibrandi, Simona, Nicocia, Giacomo, Rinaldi, Carmela, Sidoti, Antonina, D’Angelo, Rosalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278727/
https://www.ncbi.nlm.nih.gov/pubmed/32413970
http://dx.doi.org/10.3390/antiox9050416