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Prodromal Intestinal Events in Alzheimer’s Disease (AD): Colonic Dysmotility and Inflammation Are Associated with Enteric AD-Related Protein Deposition

Increasing evidence suggests that intestinal dysfunctions may represent early events in Alzheimer’s disease and contribute to brain pathology. This study examined the relationship between onset of cognitive impairment and colonic dysfunctions in a spontaneous AD model before the full development of...

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Detalles Bibliográficos
Autores principales: Pellegrini, Carolina, Daniele, Simona, Antonioli, Luca, Benvenuti, Laura, D’Antongiovanni, Vanessa, Piccarducci, Rebecca, Pietrobono, Deborah, Citi, Valentina, Piragine, Eugenia, Flori, Lorenzo, Ippolito, Chiara, Segnani, Cristina, Palazon-Riquelme, Pablo, Lopez-Castejon, Gloria, Martelli, Alma, Colucci, Rocchina, Bernardini, Nunzia, Trincavelli, Maria Letizia, Calderone, Vincenzo, Martini, Claudia, Blandizzi, Corrado, Fornai, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278916/
https://www.ncbi.nlm.nih.gov/pubmed/32429301
http://dx.doi.org/10.3390/ijms21103523