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Dual Deep Sequencing Improves the Accuracy of Low-Frequency Somatic Mutation Detection in Cancer Gene Panel Testing

Cancer gene panel testing requires accurate detection of somatic mosaic mutations, as the test sample consists of a mixture of cancer cells and normal cells; each minor clone in the tumor also has different somatic mutations. Several studies have shown that the different types of software used for v...

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Detalles Bibliográficos
Autores principales: Ura, Hiroki, Togi, Sumihito, Niida, Yo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278996/
https://www.ncbi.nlm.nih.gov/pubmed/32429412
http://dx.doi.org/10.3390/ijms21103530