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Functional Block of Interleukin-6 Reduces a Bone Pain Marker But Not Bone Loss in Hindlimb-Unloaded Mice

Interleukin-6 (IL-6) is widely accepted to stimulate osteoclasts. Our aim in this study was to examine whether the inhibitory effect of IL-6 on bone loss and skeletal pain associated with osteoporosis in hindlimb-unloaded (HU) mice in comparison with bisphosphonate. Eight-week-old male ddY mice were...

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Detalles Bibliográficos
Autores principales: Wakabayashi, Hiroki, Miyamura, Gaku, Nagao, Nobuto, Kato, Sho, Naito, Yohei, Sudo, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278999/
https://www.ncbi.nlm.nih.gov/pubmed/32429268
http://dx.doi.org/10.3390/ijms21103521