Dual Targeting of Stromal Cell Support and Leukemic Cell Growth by a Peptidic PKC Inhibitor Shows Effectiveness against B-ALL

Mesenchymal stem cells (MSC) favour a scenario where leukemic cells survive. The protein kinase C (PKC) is essential to confer MSC support to leukemic cells and may be responsible for the intrinsic leukemic cell growth. Here we have evaluated the capacity of a chimeric peptide (HKPS), directed again...

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Detalles Bibliográficos
Autores principales: Ruiz-Aparicio, Paola Fernanda, Vanegas, Natalia-Del Pilar, Uribe, Gloria Inés, Ortiz-Montero, Paola, Cadavid-Cortés, Camila, Lagos, Jimmy, Flechas-Afanador, Jessica, Linares-Ballesteros, Adriana, Vernot, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279155/
https://www.ncbi.nlm.nih.gov/pubmed/32466311
http://dx.doi.org/10.3390/ijms21103705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279155/
https://www.ncbi.nlm.nih.gov/pubmed/32466311
http://dx.doi.org/10.3390/ijms21103705

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