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Genetics and Sex in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS): Is There a Link?

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no known cure. Approximately 90% of ALS cases are sporadic, although multiple genetic risk factors have been recently revealed also in sporadic ALS (SALS). The pathological expansion of a hexanucleotide repeat in chromosom...

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Detalles Bibliográficos
Autores principales: Trojsi, Francesca, D’Alvano, Giulia, Bonavita, Simona, Tedeschi, Gioacchino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279172/
https://www.ncbi.nlm.nih.gov/pubmed/32455692
http://dx.doi.org/10.3390/ijms21103647