Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia

INTRODUCTION: Synapse dysfunction is emerging as an early pathological event in frontotemporal dementia (FTD), however biomarkers are lacking. We aimed to investigate the value of cerebrospinal fluid (CSF) neuronal pentraxins (NPTXs), a family of proteins involved in homeostatic synapse plasticity,...

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Detalles Bibliográficos
Autores principales: van der Ende, Emma L, Xiao, Meifang, Xu, Desheng, Poos, Jackie M, Panman, Jessica L, Jiskoot, Lize C, Meeter, Lieke H, Dopper, Elise GP, Papma, Janne M, Heller, Carolin, Convery, Rhian, Moore, Katrina, Bocchetta, Martina, Neason, Mollie, Peakman, Georgia, Cash, David M, Teunissen, Charlotte E, Graff, Caroline, Synofzik, Matthis, Moreno, Fermin, Finger, Elizabeth, Sánchez-Valle, Raquel, Vandenberghe, Rik, Laforce Jr, Robert, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B, Butler, Christopher R, Ducharme, Simon, Gerhard, Alex, Danek, Adrian, Levin, Johannes, Pijnenburg, Yolande AL, Otto, Markus, Borroni, Barbara, Tagliavini, Fabrizio, de Mendonca, Alexandre, Santana, Isabel, Galimberti, Daniela, Seelaar, Harro, Rohrer, Jonathan D, Worley, Paul F, van Swieten, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Neurodegeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279197/
https://www.ncbi.nlm.nih.gov/pubmed/32273328
http://dx.doi.org/10.1136/jnnp-2019-322493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279197/
https://www.ncbi.nlm.nih.gov/pubmed/32273328
http://dx.doi.org/10.1136/jnnp-2019-322493

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