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Increased extracellular vesicles mediate inflammatory signalling in cystic fibrosis

RATIONALE: Mutations in the cystic fibrosis transmembrane regulator (CFTR) gene form the basis of cystic fibrosis (CF). There remains an important knowledge gap in CF as to how diminished CFTR activity leads to the dominant inflammatory response within CF airways. OBJECTIVES: To investigate if extra...

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Detalles Bibliográficos
Autores principales: Useckaite, Zivile, Ward, Mark P, Trappe, Anne, Reilly, Rebecca, Lennon, Jenny, Davage, Holly, Matallanas, David, Cassidy, Hilary, Dillon, Eugene T, Brennan, Kiva, Doyle, Sarah L, Carter, Suzanne, Donnelly, Seamas, Linnane, Barry, McKone, Edward F, McNally, Paul, Coppinger, Judith A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279202/
https://www.ncbi.nlm.nih.gov/pubmed/32265339
http://dx.doi.org/10.1136/thoraxjnl-2019-214027