Exogenous Therapeutics of Microrna-29a Attenuates Development of Hepatic Fibrosis in Cholestatic Animal Model through Regulation of Phosphoinositide 3-Kinase p85 Alpha

Recent studies have found that microRNA-29a (miR-29a) levels are significantly lower in fibrotic livers, as shown with human liver cirrhosis. Such downregulation influences the activation of hepatic stellate cells (HSC). Phosphoinositide 3-kinase p85 alpha (PI3KP85α) is implicated in the regulation...

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Detalles Bibliográficos
Autores principales: Yang, Ya-Ling, Wang, Feng-Sheng, Lin, Hung-Yu, Huang, Ying-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279217/
https://www.ncbi.nlm.nih.gov/pubmed/32455716
http://dx.doi.org/10.3390/ijms21103636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279217/
https://www.ncbi.nlm.nih.gov/pubmed/32455716
http://dx.doi.org/10.3390/ijms21103636

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