Similarity-Based Methods and Machine Learning Approaches for Target Prediction in Early Drug Discovery: Performance and Scope

Computational methods for predicting the macromolecular targets of drugs and drug-like compounds have evolved as a key technology in drug discovery. However, the established validation protocols leave several key questions regarding the performance and scope of methods unaddressed. For example, pred...

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Detalles Bibliográficos
Autores principales: Mathai, Neann, Kirchmair, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279241/
https://www.ncbi.nlm.nih.gov/pubmed/32438666
http://dx.doi.org/10.3390/ijms21103585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279241/
https://www.ncbi.nlm.nih.gov/pubmed/32438666
http://dx.doi.org/10.3390/ijms21103585

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