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Role of the Ang2–Tie2 Axis in Vascular Damage Driven by High Glucose or Nucleoside Diphosphate Kinase B Deficiency

Ablation of nucleoside diphosphate kinase B (NDPK-B) in mice causes a breakdown of the neurovascular unit in the retina, mimicking diabetic retinopathy. The NDPK-B deficiency-induced vascular damage is mediated by excessive angiopoietin 2 (Ang2). Herein, the potential involvement of its receptor, Ti...

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Detalles Bibliográficos
Autores principales: Chatterjee, Anupriya, Eshwaran, Rachana, Huang, Hongpeng, Zhao, Di, Schmidt, Martina, Wieland, Thomas, Feng, Yuxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279316/
https://www.ncbi.nlm.nih.gov/pubmed/32466219
http://dx.doi.org/10.3390/ijms21103713